IITC 钳式测痛仪是根据 Randall-Selitto 理论设计是进行炎症足加压实验的经典仪器。

型号2450型

根据 Randall-Selitto 法将药物添加在小实验动物的炎症足上。Randall-Selitto 测痛仪测量单元具有压力传感器并通过液晶屏实时显示测量参数。压力施加器一端为弹性的尖形探头另一端平坦。使用时将动物足部放入压力施加器中间对准探头施加压力。逐步提高作用于动物爪子上的机械压力逼近动物的疼痛阈限当动物出现缩足反应时仪器自动测量并记录压力信号以g为单位。

与热痛不同该仪器用于机械压痛和钝痛的痛觉测量常用于辨别左右爪不同的痛觉反应。

钳式测痛仪的产品特点

适用于大鼠和小鼠精确度为0.01克
压力400克数字显示功能实时压力、值单位为g
配置脚踏控制器控制启动下次实验解放双手提高实验效率可选的动物固定支架可轻松固定动物
方便操作测量误差小于0.5%不需校准采用RS-232输出方式

钳式测痛仪 Rodent Pincher Analgesia Meter 

Rodent Pincher allows researchers to measure and test pain threshold in a simple, accurate method when measuring pain nociception.

The system can be used on mice or rats and will measure and display in grams the amount of force that has been applied to the animals paw.

Accuracy is .01 grams, no calibration needed.

One year warranty, CE certified

相关文献

[HTML] Coupled activation of primary sensory neurons contributes to chronic pain

YS Kim, M Anderson, K Park, Q Zheng, A Agarwal… - Neuron, 2016 - Elsevier

… reported low incidence of neuron-neuron dye-coupling after CFA injection in the mouse paw
and … of naive, CFA, CFA with CBX, sham, SN-CCI, and SN-CCI with CBX animals by rodent pincher … CreER mice, which is present in glial cells in the peripheral nervous system such as …

[HTML] Imaging large-scale cellular activity in spinal cord of freely behaving mice

KJ Sekiguchi, P Shekhtmeyster, K Merten… - Nature …, 2016 -

… was recorded during rest (left) and following cutaneous stimulation with a rodent pincher applied
to … Mouse running speed (black) and tail pinch application (purple) is shown on top … Previous studies
in anaesthetized rodents, using two-photon imaging of non-selective synthetic or …

Effects of primary and recurrent sacral chordoma on the motor and nociceptive function of hindlimbs in ratsan orthotopic spine model

R Sarabia-Estrada, A Ruiz-Valls, SR Shah… - … of NeurosurgerySpine, 2017 - thejns.org

… Nociceptive response was evaluated using the rodent pincher analgesia meter (Part # 2450,
IITC Life Science … chordoma models derived from human tissues have been used to produce rodent
tumors; however … is a lack of studies on pathologic gait due to chordomas in rodents …

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