面部疼痛评估仪主要应用

用来自动测量脸部受到冷热刺激的痛苦评价大鼠、小鼠的三叉神经疼痛。

当动物的脸颊触碰到双半导体控制的温度计时获得液体奖励。当温度变的过热或过冷动物就会离开。同时软件会自动记录舔的次数接触的温度计的次数和液体的摄入量。

面部疼痛评估仪的主要特点

可精确控制热或冷的温度

高效率

适用于与小鼠和大鼠

金属底座,易于清洗。

通过USB端口接连到电脑。

ANY-maze软件将分析所有的数据将实时显示和跟踪温度变化与变温器的触碰次数、舔的次数和奖赏瓶的联系。完成测试后,软件将显示图表和统计分析的实验。

orofacial Pain Assessment Device (opad)

The Stoelting OroFacial Pain Assessment Device (OPAD) provides an automated measurement of hot or cold orofacial pain assessment in the trigeminal nerve in rats and mice. Using an operant behavior conflict paradigm, rodents voluntarily decide between receiving a reward or escaping an aversive stimulus.

The Stoelting OroFacial Pain Assessment Device (OPAD) provides an automated measurement of hot or cold orofacial pain assessment in the trigeminal nerve in rats and mice. Using an operant behavior conflict paradigm, rodents voluntarily decide between receiving a reward or escaping an aversive stimulus.

The OPAD begins to work when the animal touches and presses between dual peltier-controlled temperature elements to obtain a liquid reward. As the temperature (hot or cold) becomes aversive, the animal can withdraw. The OroFacial Software will automatically track, the number of licks, contact with elements, and amount of liquid consumed.

产品特点:

　　Hot or Cold Temperature Control

　　Objective Pain Assessment

　　Operant Testing and Measures

　　High Throughput

　　Rackable System

　　Up to 16 Cages with a Single Computer

　　4° to 75°C Temperature Range

　　Easy to Clean

　　Easy USB Connection

　　Designed for use with Mice and Rats

硬件

The OPAD cage for either mice or rats is seated on a metal base that is easily cleaned. A metal rack is enclosed and can be removed and cleaned between animals. Animals are trained and tested in the cage; the reward bottle is positioned to allow access when simultaneously contacting the thermode with its orofacial region. The metal spout is connected to the data acquisition for recording each lick, in addition, contact with the thermode will record every touch and duration, finally the amount (grams) of consumption from the reward bottle is also recorded. Each cage is easily attached to computer via USB port.

　　Easy to clean

　　Thermode adjustable

　　Single cage for mice and rats

　　LCD display

　　Bottle can be moved easily

　　Easy On/Off

软件

All of this data taken from the hardware will then be displayed and analyzed using the OroFacial Software, a module of our popular ANY-maze software. The software will display and track in real-time the following eventstemperature changes and contacts with the thermode, licks and weight of the reward bottle (Figure 1). Following completion of the test, the OroFacial Software will display graphs (Figure 2) and statistical analysis of the experiment(s) (Figure 3); of course data can be downloaded to other software programs.

　　The following functions are available with the Orofacial Software:

　　Set and change thermode temperature

　　Automatically tracks licks, and touches to reward bottle & thermode

　　Ability to ramp temperature during experiment

　　Graphs and statistical analysis available

　　Up to 16 cages with a single computer

　　Easy to use interface and protocol set-up