详细介绍
鼠爪肿胀测定仪（肢体肿胀测试仪鼠爪炎症测试Plethysmometer Paw Volume Meter for Mice and Rats）（测试评估大鼠或小鼠后肢的痛觉和发炎测量精准更多详情敬请）
型号520MR
鼠爪体积测量仪用来衡量消炎药的有效性。使用时讲大鼠、小鼠的爪子浸入含有特殊细胞的水中由于浸泡水的压力发生了变化。压力的变化会被校准并显示在特殊的电子监视器上。这种检测形式可以消除由于重复浸入发生导电性的改变而产生的改变这种情况在类似的其他仪器上发现过。测试结果直接显示在LCD上（大鼠精确到0.01毫升、小鼠精确到0.001毫升）。无论是用电池还是用9V或12V的适配器该设备表现稳定操作安全。
Paw Volume Meter enables researchers to measure the effectiveness of anti-inflammatory agents and agents to reduce edemic conditions. In use, the paw is inserted into plain water, which contains a special water cell of which the pressure is changed due to the immersion. This pressure change is calibrated in ml and shown on a special electronic monitor. This form of detection eliminates changes due to conductivity alterations at repeated insertions as found on comparable units. The measurements are shown on the units LCD readout in .01ml for rats and .001ml for mice. The unit is stable and can be safely operated either on its own battery or on a line adapter at 9 or 12 V. The unit is stable and can be safely operated either on its own battery or on a line adapter at 9 or 12 V.
鼠爪肿胀测定仪主要特点
Ø No wetting solution needed
Ø One calibration/yr.
Ø Battery operated
鼠爪肿胀测定仪型号参数
| Part # | Description |
| 520MR | Plethysmometer (Paw Volume) Meter Mice Rat |
| 520A | Plethysmometer - Water Cell, Plexi-Glas, Cable Only |
| |
部分参考文献
IITC鼠爪肿胀仪被各研究单位广泛应用在各类专业期刊如《Pain》《Neuroscience》《Behavioural brain research》《Molecular Cancer Therapeutics》等国际杂志上发表了数千篇论文。
Exploring the role of nociceptor-specific sodium channels in pain transmission using Na v 1.8 and Na v 1.9 knockout mice
S Leo, R D'Hooge, T Meert - Behavioural brain research, 2010 - Elsevier
... a withdrawal response was calculated for each animal from three measurements on both hind
paws. ... inflammatory response produced by CFA, paw edema was measured using a
plethysmometer (IITC Inc ... acetone was sprayed onto the plantar surface of the left hind paw with ...
Delta opioid receptor‐mediated analgesia is not altered in preprotachykinin A knockout mice
D Dubois, L Gendron - European Journal of Neuroscience, 2010 - Wiley Online Library
... Behavioral testing. Plethysmometer. To evaluate the level of inflammation induced by CFA
injection in PPTA −/− and PPTA +/+ mice, the volume of the hind limbs was measured using
a plethysmometer (IITC Life Science Inc., Woodlａnd Hills, CA, USA). ...
Effects of an acetone extract of Boswellia carterii Birdw.(Burseraceae) gum resin on adjuvant-induced arthritis in lewis rats
AY Fan, L Lao, RX Zhang, AN Zhou, LB Wang… - Journal of …, 2005 - Elsevier
... et al., 1997). Paw volume was measured every other day between days 16 and 24
with a plethysmometer (IITC Inc., Woodlａnd Hills, CA), which consists of two vertical,
interconnected, water-filled Perspex cells. The paw to be ...
Cannabinoids attenuate cancer pain and proliferation in a mouse model
N Saghafi, DK Lam, BL Schmidt - Neuroscience letters, 2011 - Elsevier
... Tumor growth was measured using a 520 M Plethysmometer (IITC Life Sciences, Woodland
Hills) to determine the paw volume. The animal's tumor-bearing paw was inserted into a water
cell, which measures the change in pressure due to immersion. ...
Nerve growth factor links oral cancer progression, pain, and cachexia
Y Ye, D Dang, J Zhang, CT Viet, DK Lam… - Molecular cancer …, 2011 - AACR
... Tumor size and body measurement. Mouse hind-paw volume was measured by using
a plethysmometer (IITC Life Science). Tongue tumor volume was calculated at the end
of the experiment by multiplying tumor length by width by thickness. ...
A nociceptive signaling role for neuromedin B
SK Mishra, S Holzman, MA Hoon - The Journal of Neuroscience, 2012 - Soc Neuroscience
... Thirty minutes after injection of peptides, paw edema was measured using a
plethysmometer (IITC) and thermal and mechanical sensitization measured by
Hargreaves and von Frey apparatus assays (Ugo Basile), respectively. ...
GJ Amabeoku, J Kabatende - Advances in pharmacological sciences, 2011 -
... 40 min. The volume of the right hind paw was measured before and then after the
injection of carrageenan at 30 min intervals for 4 h by volume displacement method
using plethysmometer (IITC Life Sciences, USA). Group II ...
Re-expression of the methylated EDNRB gene in oral squamous cell carcinoma attenuates cancer-induced pain
CT Viet, Y Ye, D Dang, DK Lam, S Achdjian, J Zhang… - PAIN®, 2011 - Elsevier
... The results of the 6 values were averaged for each paw for that day. Paw volume measurements
were performed with a plethysmometer (IITC Life Sciences). The paw was inserted into a water
cell, of which the pressure is changed due to the immersion. ...
Studies on anti-inflammatory and analgesic activities of betel nut in rodents
S Khan, MH Mehmood, ANA Ali, FS Ahmed… - Journal of …, 2011 - Elsevier
... After 30 min of treatment, 50 μl of 1% carrageenan was administered into the sub-plantar side
of the right hind paw. The volume of the right hind paw was measured (Winter et al., 1962) using
a plethysmometer (IITC Inc. Life Sciences, Woodlａnd Hills, CA). ...
Antimicrobial and anti-inflammatory activities of Pterygota macrocarpa and Cola gigantea (Sterculiaceae)
C Agyare, GA Koffuor, VE Boamah, F Adu… - Evidence-Based …, 2012 -
... groups ( ). The initial foot volumes of the chicks were measured using plethysmometer
(IITC Life Science Inc., CA, USA) after which 0.01 mL of 2% carrageenan was injected
into the plantar of the right foot to induce inflammation. The ...
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